Allergic asthma and viral wheezing
Conditions
Interventions
control group:Given inhaled corticosteroids, short-acting ß2 receptor agonists can be used as needed to relieve asthma and acute wheezing symptoms.
observer group:On the basis of the control group, levocetirizine hydrochloride oral solution was given once a day, 1.25 mg ( 2.5 ml ) each time.
Sponsors
West China Second Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
0.5 Years to 2 Years
Inclusion criteria
Inclusion criteria: 1.Age 6 months to 2 years ( including boundary age ), regardless of gender ; 2.Children with wheezing symptoms and clinical diagnosis of asthma or viral wheezing ; 3.There is a history of personal allergies, allergic diseases including atopic dermatitis, allergic rhinitis, gastrointestinal allergies, urticaria, food allergies ; 4.Specific IgE detection of allergens or skin prick test was positive ; 5.To obtain the written consent of the guardian ; 6.Can be written by the guardian of the patient diary card
Exclusion criteria
Exclusion criteria: 1.Oral glucocorticoid drugs were used within 7 days before enrollment ; 2.Oral antihistamines were used within 3 days before enrollment ; 3.Children who are allergic to the components of levocetirizine hydrochloride preparations or piperazine derivatives such as hydroxylazine, cetirizine, and cyclazine or have a history of allergy ; 4.Children with snoring and diagnosed adenoidal hypertrophy have airway structural abnormalities, congenital heart disease, bronchopulmonary dysplasia, bronchiectasis, bronchial foreign body, tuberculosis and other diseases that may affect wheezing ; 5.Children with mental illness, hematological diseases, systemic infectious diseases and malignant tumors ; 6.People who are participating in other clinical trials or have participated in other clinical trials in the past 3 months ; 7.Investigators judged that children who were not suitable for inclusion in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Therapeutic effectiveness; | — |
Secondary
| Measure | Time frame |
|---|---|
| Wheezing symptom score;total nasal symptom score;Skin symptom score;VAS score;Use of inhaled short-acting ß2 receptor agonists; | — |
Countries
China
Contacts
Public ContactLiu hanmin
West China Second Hospital of Sichuan University
Outcome results
None listed