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Screening of miRNA in different pathological stages of gastric mucosal " inflammation-cancer " transformation and its correlation with deficiency syndrome

Screening of miRNA in different pathological stages of gastric mucosal " inflammation-cancer " transformation and its correlation with deficiency syndrome

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400092019
Enrollment
Unknown
Registered
2024-11-07
Start date
2022-10-18
Completion date
Unknown
Last updated
2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric precancerous lesions

Interventions

chronic superficial gastritis:None
Hp positive atrophic gastritis of gastric antrum:None
Atrophic gastritis of gastric antrum with intestinal metaplasia:None
Atrophic gastritis of the sinus with intestinal metaplasia:None
Atrophic gastritis with dysplasia:None

Sponsors

Xiyuan Hospital of the Chinese Academy of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) Patients with chronic non atrophic gastritis, atrophic gastritis, intestinal metaplasia, and dysplasia confirmed by gastroscopy histopathology; (2) Age range from 18 to 75 years old; (3) The subject is informed and voluntarily signs an informed consent form;

Exclusion criteria

Exclusion criteria: (1) Individuals with a history of gastric ulcers, gastric polyps, and gastric surgery; (2) Suspected of advanced gastric cancer or other systemic malignancies; (3) Patients with concomitant primary diseases such as heart, cerebrovascular, liver, kidney, and hematopoietic system; (4) Subjects with severe anxiety and depression; (5) Individuals with intellectual, comprehension, or language impairments.

Design outcomes

Primary

MeasureTime frame
MicroRNA;G-17;PG I;PG II;Helicobacter pylori antibody;

Countries

China

Contacts

Public ContactWEN Yandong

Xiyuan Hospital of the Chinese Academy of Traditional Chinese Medicine

wen6210@126.com+86 186 0020 9185

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026