Tumor
Conditions
Interventions
Control groups:Conventional management
Intervention group:Overall management:
Sponsors
Zhejiang Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Agree to join the group and sign the informed consent; 2. Use immune checkpoint inhibitors; 3. Age 18 and above, regardless of gender; 4. Pathological diagnosis of malignant tumor; 5.ECOG PS score 0-1; 6. Liver function: For patients without liver primary or metastatic tumors, ALT, AST and ALP should be =90ml/min are required before ICIs treatment; Patients with primary or metastatic renal tumors were required to have creatinine =60ml/min. 8. The expected survival is greater than 3 months.
Exclusion criteria
Exclusion criteria: 1.Patients with serious underlying diseases, including symptomatic congestive heart failure, myocardial infarction, cerebral infarction, and interstitial lung disease before screening; 2.Patients with acute infection; 3.Patients who are difficult to cooperate with the implementation of the program, such as patients with consciousness disorders or cognitive disorders, patients with mental disorders, patients who can not receive follow-up as planned; 4.Pregnant or lactating women; 5.Other conditions that researchers believe are not suitable for participation, such as poor compliance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 24h treatment rate of adverse reactions; | — |
Secondary
| Measure | Time frame |
|---|---|
| Permanent discontinuation rate due to adverse reactions;Time of discovery of new adverse reactions;Mortality due to adverse reactions;Patient Quality of life (EQ-5D);Adverse reaction treatment time;Incidence of adverse reactions; | — |
Countries
China
Contacts
Public ContactZheng Xiaowei
Zhejiang Provincial People's Hospital
Outcome results
None listed