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A study on the correlation between SK2,C1q/tumour necrosis factor-related protein-3,heat shock protein47and imaging indicators of myocardial fibrosis in patients with cardiomyopathy

A study on the correlation between sK2,CTRP3,HSP47and imaging indicators of myocardial fibrosis in patients with cardiomyopathy

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400092017
Enrollment
Unknown
Registered
2024-11-07
Start date
2023-01-08
Completion date
Unknown
Last updated
2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertrophic cardiomyopathy Dilated cardiomyopathy

Interventions

Dilated cardiomyopathy group:NA
Hypertrophic cardiomyopathy group:NA

Sponsors

The second Affiliated Hosrital of Gannan Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Age range from 20 to 70 years old; 2. Patients with dilated cardiomyopathy meet the diagnostic criteria in the 2018 Chinese Guidelines for the Diagnosis and Treatment of Dilated Cardiomyopathy; 3. patients with hypertrophic cardiomyopathy meet the diagnostic and treatment guidelines for adult hypertrophic cardiomyopathy in China; 4. All patients have undergone cardiac magnetic resonance enhanced scanning; 5. All patients have complete clinical data and corresponding auxiliary examination results; 6. The patient and their family members have informed consent and signed an informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients with liver, kidney, lung and other organ fibrosis diseases; 2. Patients with connective tissue diseases or malignant tumors; 3. Severe liver and kidney dysfunction; 4. Incomplete clinical data. 5. Patients with heart valve disease.

Design outcomes

Primary

MeasureTime frame
Plasma concentrations of sK2 and CTRP3;HSP47 concentration;left ventricular ejection fraction, Left;left ventricular end-diastolic dimension, LVEDD;Right ventricular end-diastolic diameter, RVD;interventricular septum thickness, IVST;Left ventricular posterior wall thickness, LVPWT;left atrial diameter, LAD;Right atrial diameter, RAD;

Countries

China

Contacts

Public ContactLu Ting

The second Affiliated Hosrital of Gannan Medical University

419695474@qq.com+86 15170607392

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026