Bronchopulmonary dysplasia of preterm infants
Conditions
Interventions
Control group:None
Sponsors
Second hospital of Jilin University
Eligibility
Sex/Gender
All
Age
No minimum to 3 Months
Inclusion criteria
Inclusion criteria: (1) Premature infants with gestational age = 32 weeks born and admitted to the neonatology department at the Second Hospital of Jilin University (GA is based on the date of the mother's last menstrual period and ultrasound examination conducted in the first three months of pregnancy). (2) No serious congenital abnormalities or genetic syndromes. (3) Obtain the consent of the guardian.
Exclusion criteria
Exclusion criteria: (1) Complex congenital heart disease; (2) Abnormalities in central nervous system, digestive tract and respiratory tract; (3) Invasive respiration support due to surgery or other reasons; (4) Other deformities, like diaphragmatic hernia, chromosomal abnormalities, etc; (5) Expected to live less than 28 days; (6) The guardian is unwilling to participate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Composition of gut microbiota in premature infants at 7 and 28 days after birth; | — |
Secondary
| Measure | Time frame |
|---|---|
| Levels of bile acid in stool samples of premature infants at 7 and 28 days after birth;Serum cytokine levels on postnatal 1, 7, 14, 21, and 28 days; | — |
Countries
China
Contacts
Public ContactYunfeng Zhang
Second hospital of Jiln University
Outcome results
None listed