Prostate puncture
Conditions
Interventions
Remimazolam Tosylate Group:Remimazolam tosylate for anesthesia induction
Etomidate group:Etomidate for anesthesia induction
Sponsors
The First Affiliated Hospital of Xi'an Jiaotong University
Eligibility
Sex/Gender
All
Age
65 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1.Age 65-85 years old; 2.NYHA heart function class I-II; 3.18kg/m^2<=BMI<=30kg/m^2 4.ASA classification I-III; 5.The patients and their families understood this study, voluntarily participated in this trial, and signed a written informed consent;
Exclusion criteria
Exclusion criteria: 1.Allergic to remimazolam tosylate or etomidate; 2.Severe renal insufficiency (dialysis required before surgery); 3.Severe liver impairment; 4.Patients with a history of mental and neurological diseases: such as depression, Parkinson's disease, basal ganglia lesions, schizophrenia, epilepsy, Alzheimer's disease, myasthenia gravis, cerebrovascular accident, etc.; 5.Patients who are considered unsuitable to participate in this trial by the researchers; 6.Participated in another study within 4 weeks before the current trial; 7.Patients with drug and alcohol abuse.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative recovery time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Vital signs at different times, HR, MAP, SpO2, BIS values;Time to successful induction of anesthesia;Incidence of respiratory depression;Incidence of hypotension;Incidence of injection pain;Incidence of agitation during the awakening period;Incidence of nausea and vomiting; | — |
Countries
China
Contacts
Public ContactYaomin Zhu
The First Affiliated Hospital of Xi'an Jiaotong University
Outcome results
None listed