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Exploration on the dose-effect relationship of ropivacaine ultrasound-guided supra-inguinal fascia iliaca compartment block for postoperative analgesia

Exploration on the dose-effect relationship of ropivacaine ultrasound-guided supra-inguinal fascia iliaca compartment block for postoperative analgesia

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400091988
Enrollment
Unknown
Registered
2024-11-07
Start date
2024-11-08
Completion date
Unknown
Last updated
2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hip disease

Interventions

ropivacaine group(Group R):Various concentrations of ropivacaine with 30mL volume
4mg dexamethasone + ropivacaine group(Group D1):4mg dexamethasone and Various concentrations of ropivacaine with 30mL volume
8mg dexamethasone + ropivacaine group(Group D2):8mg dexamethasone and Various concentrations of ropivacaine with 30mL volume

Sponsors

Chongqing Traditional Chinese Medicine Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Aged 18-80 years. 2. ASA grade I - III, no gender limitation. 3.Patients who underwent the first Total hip arthroplasty, join the research voluntary and obtained informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with BIM=18 or =35; 2. Allergic to related drugs; 3. Inability to cooperate with pain evaluators; 4. Severe heart, lung, liver and kidney disease; 5. Diabetic peripheral neuropathy; 6. Patients with chronic pain treatment; 7. Patients regularly take corticosteroid drugs; 8. Persons addicted to alcohol or drugs; 9. Persons with serious mental illness; 10. Pregnant women; 11. Patients with contraindications to nerve block puncture.

Design outcomes

Primary

MeasureTime frame
Score of Visual analogue scale ;

Secondary

MeasureTime frame
Score of Bromage;Success rate of S-FICB;Remifentanil dosage;PCIA dosage;Press times of PCIA;The time of the first tramadol supplement;Percentage of patients requiring tramadol supplementation within 6 hours;

Countries

China

Contacts

Public ContactQIN ZHANG

Chongqing Traditional Chinese Medicine Hospital

zhangyp8415@163.com+86 152 2304 9366

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026