sepsis
Conditions
Interventions
sepsis group:None
Sponsors
Fujian Medical University Union Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: The sepsis group included: 1. From October 2024 to October 2025, patients were admitted to the emergency Department and Emergency intensive Medicine Department of Yushan Hospital, Union Hospital Affiliated to Fujian Medical University; 2. Patients =18 years old 3. Patients diagnosed with sepsis. Patients meeting the diagnostic criteria for sepsis and septic shock as defined in Sepsis 3.0 were included. 4. The patient received standardized treatment for sepsis. The healthy control group was healthy volunteers from the Health Examination Center of Union Hospital Affiliated to Fujian Medical University and matched with the age and sex of sepsis patients from October 2024 to October 2025. The Bristol Stool Score is 4-5 points.
Exclusion criteria
Exclusion criteria: Exclusion criteria for sepsis group: 1. Active malignant tumor or history of malignant tumor and use of antitumor drugs; 2. 2. Acquired immune deficiency syndrome; 3. History of autoimmune disease; 4. Combined with enterostomy; 5. Gastrointestinal bleeding or cirrhosis; 6. History of end-stage renal disease or hemodialysis; 7. Cardiopulmonary resuscitation before admission; 8. Poisoning; 9. Pregnancy and perinatal period; 10. Use of antibiotics in the past 3 months. Exclusion criteria for healthy control group: 1. History of antibiotic treatment, constipation and diarrhea in the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pulse Wave Velocity;Echocardiographic ejection fraction;Lactate;Clinical outcome; | — |
Secondary
| Measure | Time frame |
|---|---|
| NT-proBNP;Troponin-I;Creatinekinaseisoenzymes;Myohemoglobin;Blood pressure;Heart rate; | — |
Countries
China
Contacts
Public ContactGuangwei Yu
Fujian Medical University Union Hospital
Outcome results
None listed