Gestational Diabetes Mellitus
Conditions
Interventions
Gold Standard:Diagnostic criteria for GDM: The oral glucose tolerance test (OGTT) results between 24 and 28 weeks of gestation are as follows: fasting plasma glucose (FPG) = 5.1 mmol/L, 1-hour plasma
Index test:Validation will be conducted by comparing the expression levels of genes from the diagnostic model in the peripheral blood of patients with gestational diabetes mellitus (GDM) and non-GDM p
Sponsors
Department of Gynecology, Linquan Maternity and Child Healthcare Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria for the Experimental Group: 1. Age = 18 years; 2. Underwent a 75g oral glucose tolerance test (OGTT) at 24-28 weeks of gestation; 3. No clear exclusion criteria. **Inclusion Criteria for the Control Group:** 1. Matched with the experimental group in terms of gestational age difference of less than 7 days, previous pregnancy history difference of less than 2 times, and the same number of previous deliveries; 2. Age = 18 years; 3. Underwent a 75g oral glucose tolerance test (OGTT) at 24-28 weeks of gestation; 4. No clear exclusion criteria.
Exclusion criteria
Exclusion criteria: Exclusion Criteria: BMI = 28 kg/m²; a first-degree relative with a history of type 2 diabetes mellitus (T2DM); history of coronary heart disease; chronic hypertension; high-density lipoprotein (HDL) 2.8 mmol/L; history of gestational diabetes mellitus (GDM) or delivery of a macrosomic infant; history of polycystic ovary syndrome (PCOS); recurrent positive fasting urinary glucose during early pregnancy; age > 45 years.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expression levels of diagnostic genes;Accuracy;Sensitivity;Specificity; | — |
Countries
China
Contacts
Public ContactShu-Guang Zhou
Department of Gynecology, Linquan Maternity and Child Healthcare Hospital
Outcome results
None listed