Acute stress disorder, post-traumatic stress disorder, postoperative stress response, postoperative sleep disorder
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Gender unlimited; 2. Age range from 18 to 70 years old; 3. BMI:18-28Kg/m^2; 4. ASA (American Society of Anesthesiologists) Grades I-III; 5. The coagulation function is normal.
Exclusion criteria
Exclusion criteria: 1. Individuals with coagulation dysfunction; 2. Individuals with immune dysfunction; 3. Long term use of immunosuppression Agent; 4. Individuals with severe organ dysfunction such as heart, liver, and kidney; 5. Accompanied by mental system diseases; 6. Individuals with a history of spinal surgery; 7. Individuals who are allergic to the drugs used in this study or Individuals with allergic constitution.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Stress response; | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS score;QoR-40 score;Consumption of remifentanil;Vital signs: mean arterial pressure (MAP), heart rate (HR);Number of compressions of analgesic pump;Headache, nausea, and vomiting occur;Stanford Acute Stress Response Questionnaire Score;operative time; | — |
Countries
China
Contacts
The second hospital of Dalian Medical University