colorectal cancer
Conditions
Interventions
Research Group:N/A
Control group:N/A
Sponsors
General Surgery Department, Qilu Hospital, Shandong University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Age above 18 years old, under 85 years old, regardless of gender; 2. Patients diagnosed with colorectal cancer by histological or cytological diagnosis and undergoing radical surgery; 3. Body mass index (BMI) 18.5-35kg/m2 (including 18.5 and 28kg/m2); (4) patients who can tolerate enteral nutrition after discharge; 5. Life expectancy of more than 3 months; 6. Patients were able to give informed consent, agreed to participate in this study and signed an informed consent form.
Exclusion criteria
Exclusion criteria: 1. The presence of severe clinical symptoms and underlying diseases may endanger the research development and follow-up; 2. Previous history of gastrointestinal surgery or other gastrointestinal treatment that affects the absorption of enteral nutrition; 3. The patient is pregnant or lactating; 4. Oral or tube feeding nutrition before surgery; (5) Patients participated in interventional clinical studies within 4 weeks before enrollment, including studies related to nutritional support; 6. Other malignant tumors in the past 5 years (except successfully treated in situ basal cell skin tumors and in situ cervical tumors); 7. The patient had abnormal liver and kidney function (alanine aminotransferase =2 times the upper limit of normal; Total bilirubin (Tbil) =2 times the upper limit of normal; Creatinine Cr=2 times upper limit of normal); 8. Known uncontrolled diabetes mellitus or fasting plasma glucose =10mmol/L; 9. The patient had a known history of hypothyroidism or hyperthyroidism; 10. The patient is using thymosin, glucocorticoid, thyroxine, growth hormone, anti-tumor necrosis factor biological agents, etc. 11. Patients or their families refused to sign the informed consent; 12. Uncontrolled mental illness; 13. Patients who were considered by the investigator to be unsuitable for the study (e.g., poor adherence).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| nutritional composition indicators;FAACT A/CS;Clinical OUTCOME MEASURES;immune-related indicators; | — |
Secondary
| Measure | Time frame |
|---|---|
| Inflammation-related indicators; | — |
Countries
China
Contacts
Public ContactZhang Wenhua
Shandong University of Qilu Hospital
Outcome results
None listed