epilepsy
Conditions
Interventions
Observation group:No intervention
Sponsors
Beijing Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: (1) patients met the latest diagnostic criteria of International League Against Epilepsy and were diagnosed with epilepsy; (2) LEV concentrations were measured at least two days after LEV treatment and before the next dose. (3) LEV plasma concentration was not lower than the quantitative lower line of the determination method; (4) No intracranial space-occupying lesions, vascular malformations or other progressive lesions were reported in cranial imaging. (5) no liver or kidney disease; (6) can accept routine blood drug concentration monitoring; (7) complete medical records.
Exclusion criteria
Exclusion criteria: Exclusion criteria: (1) The time point of blood collection did not conform to the design of this study, and the plasma concentration did not reach the steady-state trough concentration; (2) if the time of last medication was not clear, or LEV had been taken on the morning of blood drawing; (3) complicated with serious mental disorders or other serious diseases of the heart, lung, liver, kidney or blood system; (4) poor compliance, unable to take medicine on time; (5) incomplete cases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MDR1 gene; | — |
Countries
China
Contacts
Public ContactBolin Zhu
Beijing Hospital
Outcome results
None listed