Neurodegenerative diseases
Conditions
Interventions
Observation group (with Parkinson's disease):none
Observation group (with Alzheimers disease):none
Sponsors
Shanghai Genaral Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 95 Years
Inclusion criteria
Inclusion criteria: PD diagnostic criteria: Parkinson's disease group meets internationally recognized diagnostic criteria: MDS clinical diagnostic criteria for Parkinson's dise30 Inclusion criteria for PD group: (1) Meet the diagnostic criteria for PD; (2) Age>18 years old; (3) Voluntarily participate in this study and sign the informed consent form. (4) No other systemic diseases, such as tumors, infectious diseases, digestive system diseases, etc. Inclusion criteria for CON group: (1) Confirmation of absence of neurodegenerative diseases; (2) Age>18 years old; (3) Voluntarily participate in this study and sign the informed consent form. (4) No other systemic diseases, such as tumors, infectious diseases, digestive system diseases, etc.
Exclusion criteria
Exclusion criteria: Two exclusion criteria: (1) Use of drugs that affect the tongue coating status within the two weeks prior to sampling (such as traditional Chinese medicine, antibiotics, antifungal drugs, etc.); (2) Suffering from diseases that affect the state of tongue coating (such as acute upper respiratory tract infection, oral ulcers, glossitis, etc.); (3) Accompanied by major diseases such as liver and kidney dysfunction, severe infections, malignant tumors, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Peak area of non targeted metabolites; | — |
Secondary
| Measure | Time frame |
|---|---|
| Tongue coating index; | — |
Countries
China
Contacts
Public ContactFan Guorong
Shanghai Genaral Hospital
Outcome results
None listed