Gastrointestinal Tumors
Conditions
Interventions
Grope P:Propofol
Grope C:Ciprofol
Sponsors
Liaoning Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients undergoing laparoscopic radical resection of gastrointestinal tumors under general anaesthesia; 2. Age 60 and above (including 60 years old); 3. Body mass index (BMI) 18.5-30kg/m^2; 4. ASA grade I-III; 5. Voluntary signing of informed consent.
Exclusion criteria
Exclusion criteria: 1.Cognitive dysfunction(MMSE=27)2.Individuals with neurological or muscular system diseases, mental illness;3.History of severe cerebrovascular disease or complication after craniocerebral trauma (e.g., emotional disorders, language disorders);4.History of sedative, antidepressant medication use, alcoholism, and drug abuse;5.Severe hypertension (controlled with medication, still in stage III or above hypertension), heart failure (NYHA > II);6.Severe bradycardia (requiring pacemaker);7.Individuals with ciprofol or propofol use contraindications; 8.Individuals who are unwilling or unable to communicate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Success rate of general anesthesia inducation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Age;Weight;ASA classification;Injection-site pain;Bradycardia;Tachycardia;Hypertension;Hypotension;Arrhythmia;Departure time;Anesthesia time;Operation time;Recovery time;Recovery time;Respiratory recovery time;Time to successful induction of general anesthesia; Success rate of general anesthesia;Blood pressure;Heart rate;Bispectral index;Nausea;Vomit;Respiratory depression;operator satisfaction;Patient satisfaction;Cognitive function;Arterial blood gas analysis;Total dosage of ciprofol or propofol;Total dosage of norepinephrine;Total dosage of remifentanil;The cost of ciprofol or propofol; | — |
Countries
China
Contacts
Public ContactWang Changming
Liaoning Provincial People's Hospital
Outcome results
None listed