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Effective dose of ciprofol combined with oliceridine fumarate in painless hysteroscopy

Effective dose of ciprofol combined with oliceridine fumarate in painless hysteroscopy

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400091853
Enrollment
Unknown
Registered
2024-11-05
Start date
2024-11-10
Completion date
Unknown
Last updated
2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Low dose group (Group L): oliceridine fumarate 0.75mg + ciprofol:Oliceridine fumarate 0.75 mg was injected 3 min preoperatively, and then the anaesthesia was completed with the use of ciprofol, pushed
Medium dose group (Group M): oliceridine fumarate 1mg + ciprofol:Oliceridine fumarate 1 mg was injected 3 min preoperatively, and then the anaesthesia was completed with the use of ciprofol, pushed th
High-dose group (Group H): oliceridine fumarate 1.25mg + ciprofol:Oliceridine fumarate 1.25 mg was injected 3 min preoperatively, and then the anaesthesia was completed with the use of ciprofol, push

Sponsors

Affiliated Shunde Hospital of Jinan University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age 18-60 years old; BMI 18-30 kg/m^2; Mallampati class I or II, no airway, head and neck condition abnormalities; ASA grade I or II; patients with elective proposed hysteroscopy; patients volunteered to participate in the study

Exclusion criteria

Exclusion criteria: Patients who refuse to participate or who are unfit to participate in this trial; allergy to ciprofol or oliceridine fumarate; severe cardiovascular, pulmonary, hepatic or renal dysfunction, or impaired adrenocortical function; history of alcohol or psychotropic or analgesic medication use within the last 24 h prior to surgery; airway hyperresponsiveness disease

Design outcomes

Primary

MeasureTime frame
Dose of cyclobenzaprine per patient for positive (+) or negative (-) response;

Secondary

MeasureTime frame
Changes in vital signs at different time points;Ratio of total cypropofol dose to anaesthesia time;Physician satisfaction;recovery time and adverse reactions post-surgery;Patient comfort and satisfaction postoperatively;

Countries

China

Contacts

Public ContactZhang Zhongqi

Affiliated Shunde Hospital of Jinan University

jxzzq11@139.com+86 137 9868 2324

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026