Respiratory disease
Conditions
Interventions
Test group:Set the dose of remifentanil according to the BCD sequential trial method, with an initial dose of 0.1mg/kg. Adjust the dose for the next patient based on whether a positive reaction occurs
Sponsors
Yan'an Hospital of Kunming City
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients undergoing painless fiberoptic bronchoscopy are of all genders, aged =65 years, FRAIL of ASA? and ?, and Frail of 3 to 5 points on the Simple Debilitation questionnaire (Frailty) scale.
Exclusion criteria
Exclusion criteria: Patients with a history of severe hepatic and renal insufficiency, respiratory failure, and cardiac insufficiency; Patients with bradycardia or sick sinus syndrome at rest before operation; Failure to maintain blood oxygen during examination and examination; Abuse or long-term use of narcotic, sedative, or analgesic drugs, and have a history of mental illness; The duration of the check exceeds 30 minutes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The dose of remazolam besylate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart rate, mean arterial pressure, SPO2, PETCO2 at each time point;Severity of choking reaction and grade of hypoxemia; | — |
Countries
China
Contacts
Public ContactYang Maiqiao
Yan'an Hospital of Kunming City
Outcome results
None listed