Emergence Agitation
Conditions
Interventions
Administration during anesthesia induction group:Hydromorphone hydrochloride 0.01 mg/kg was given during anesthesia induction.
Administration before the end of surgery group:Hydromorphone hydrochloride 0.01 mg/kg was given 10 minutes before the end of the surgery.
NS group:Equal volumes of 0.9% sodium chloride injection were given
Fentanyl group:When the children were diagnosed with EA in the PACU, they were intravenously injected with0 .5 µg/kg
fentanyl and 1 mg/kg propofol.
Hydromorphone group:When the patient was diagnosed with EA in the PACU , intravenous injection of 5 µg/kg hydromorphone and 1 mg/kg propofol was given.
Sponsors
Linyi People's Hospital
Eligibility
Sex/Gender
All
Age
3 Years to 7 Years
Inclusion criteria
Inclusion criteria: Part one: a. Age 3-7 years; b. Children undergoing elective tonsillectomy (or with adenoids) under seoflurane anesthesia; c. American Society of Anesthesiologists (ASA) class I-II. Part two: a. Children who developed emergence agitation tonsillectomy (and/or adenoids) surgery; b. Age 3-7 years; c. ASA class I-II.
Exclusion criteria
Exclusion criteria: First part: a. Patients with a history of heart and lung diseases; b. Patients with a history of neurological or psychiatric diseases; c.Those who are allergic to the drugs used; d. Those with liver and kidney dysfunction; e. Surgical procedures lasting more than 1 hour. Second part: a. Patients with a history of heart and lung diseases; b. Patients with a history of neurological or psychiatric diseases; c. Those who are allergic to the drugs used; d. Those with liver and kidney dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PAED scale (Part One);PAED score (Part Two);The Recurrence Rate of Agitation (Part Two);The number of times propofol is added (Part Two);The total amount of propofol used (Part Two); | — |
Secondary
| Measure | Time frame |
|---|---|
| FLACC scale (Part One);Ramsay scale (Part One);heart rate, HR (Part One);mean arterial pressure, MAP (Part One);SPO2 (Part One);Total number of cases with additional propofol after surgery (Part One);Extubation time (Part One);Time of leaving PACU (Part One);FLACC Scale (Part Two);Ramsay Scale (Part Two);heart rate, HR (Part Two);SPO2 (Part Two);blood pressure, BP (Part Two); | — |
Countries
China
Contacts
Public ContactXiming Li
Linyi People's Hospital
Outcome results
None listed