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Exploring the comparative effects of general anesthesia combined with intrathecal injection of morphine/nerve block for thoracoscopic surgery and the optimal dose of morphine

Exploring the comparative effects of general anesthesia combined with intrathecal injection of morphine/nerve block for thoracoscopic surgery and the optimal dose of morphine

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400091838
Enrollment
Unknown
Registered
2024-11-05
Start date
2024-11-05
Completion date
Unknown
Last updated
2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pain

Interventions

Experimental group 1 (0.15mg morphine):NA
Experimental group 2 (0.20mg morphine):NA
Experimental group 3 (0.25mg morphine):NA
Experimental group 4 (nerve block group):NA
Control group (conventional intravenous analgesia group):NA

Sponsors

The Fourth Affiliated Hospital of Harbin Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Electively perform thoracoscopic surgery under anesthesia and sign an informed consent form; 2.Age range of 18-65 years old, American anesthesiologist classification I-II; 3.Those who have not taken analgesics, sedatives or are allergic to them within 72 hours before surgery; 4.The anesthesia time is 1-4 hours; 5.Willing to cooperate with research and postoperative follow-up;

Exclusion criteria

Exclusion criteria: 1.Unable to communicate and cooperate before surgery, resulting in coma, severe dementia, severe mental disorders, etc; 2.Patients with obvious liver, liver and kidney dysfunction and intolerance to surgery; 3.Patients with poor compliance, coagulation dysfunction, spinal deformities, infection at the puncture site, and difficulty cooperating with the puncture operation to complete treatment; 4.Unexpected drug allergy during surgery, switch to open surgery; 5.Unable to follow up within three days after surgery;

Design outcomes

Primary

MeasureTime frame
Observation of intraoperative remifentanil dosage and postoperative 72 hour VAS score;

Secondary

MeasureTime frame
Postoperative dizziness, respiratory depression, nausea and vomiting, urinary retention, catheter-related bladder discomfort (CRBD), skin itching, hypotension and other adverse reactions related to na;

Countries

China

Contacts

Public ContactXuesong Ma

The Fourth Affiliated Hospital of Harbin Medical University

mxs13613630888@163.com+86 13613630888

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026