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A nurse-led lifestyle modification intervention for enhancing self-efficacy, illness perception, self-care management and steatosis grade among patients with metabolic dysfunction-associated steatotic liver disease: A pilot randomised controlled trial

A nurse-led lifestyle modification intervention for enhancing self-efficacy, illness perception, self-care management and steatosis grade among patients with metabolic dysfunction-associated steatotic liver disease: A pilot randomised controlled trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400091825
Enrollment
Unknown
Registered
2024-11-04
Start date
2024-11-04
Completion date
Unknown
Last updated
2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

MASLD

Interventions

intervention:lifestyle modification intervention
Control group:Usual care

Sponsors

Prince of Wales Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria include patients who are: (1) diagnosed with MASLD; (2) not in decompensated stage presented with ascites, hepatic encephalopathy or variceal haemorrhage (3) aged over 18; (4) able to understand spoken Cantonese and read Chinese; and (5) consent to participate.

Exclusion criteria

Exclusion criteria: Those with the following conditions will be excluded: (1) with other chronic liver disease; (2) with cancer, chronic kidney disease, psychiatric disorder or previous cardiovascular events. The exclusion criteria were set because other chronic liver diseases may affect the blood results and transient elastography measurement, which may underestimate the effect of the intervention on the MASLD conditions. Furthermore, the diet regimen of patients with cancer or chronic kidney disease is usually special, and general recommendations of diet modification may not be suitable for them. Besides, counselling of patients with psychiatric disorders usually requires specific techniques from trained healthcare providers, and their ability to understand information and complete the questionnaires may be affected. On the other hand, patients with a history of cardiovascular events are recommended to undergo a cardiac rehabilitation programme which recommends specific strength of physical activity according to patients’ conditions.

Design outcomes

Primary

MeasureTime frame
self-efficacy;

Secondary

MeasureTime frame
illness perceptions;self-management behaviours;steatosis grade;

Countries

HKSAR

Contacts

Public ContactMa Angel Cho Kan

Prince of Wales Hospital

1007620541@link.cuhk.edu.hk+852 9041 2039

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026