Stage B HCC patients undergoing initial TACE treatment
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age over 18 years; 2.Diagnosed with HCC confirmed by imaging or pathology; 3.Stage B according to the Barcelona Clinic Liver Cancer (BCLC) staging system; 4.Undergoing initial interventional therapy; 5.Provided informed consent and agreed to participate in the study;
Exclusion criteria
Exclusion criteria: 1.Prior to interventional therapy, the patient has undergone surgery, radiofrequency ablation, radiotherapy, or targeted drug therapy; 2.History of other malignant tumors; 3.Severe hepatic dysfunction (Child-Pugh Class C), including jaundice, hepatic encephalopathy, or refractory ascites; 4.Uncorrectable coagulopathy; 5.Renal impairment, with serum creatinine >2 mg/dL or creatinine clearance <30 mL/min; 6.Contraindications to magnetic resonance imaging (MRI), such as claustrophobia or metallic implants;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Prognosis;The area under the curve (AUC);Accuracy;Sensitivity;Specificity; | — |
Secondary
| Measure | Time frame |
|---|---|
| treatment response;Evaluation of imaging quality by MTT-DCE; | — |
Countries
China
Contacts
Tongji Hospital, Tongji Medical College ,Huazhong University of Science and Technology