Alzheimer's disease
Conditions
Interventions
Experimental group:Administration of Bifidobacterium animalis subsp. lactis Probio-M8 combined drug (access to standardised treatment), once daily, one bag at a time for 3 months.
control group:Administration of a placebo without Bifidobacterium animalis subsp. lactis Probio-M8 combined drug (access to standardised treatment), once daily, one bag at a time for 3 months.
Sponsors
Affiliated Hospital of Inner Mongolia Medical University
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Voluntarily sign the informed consent form; 2. Age range is 50-80 years old; 3. No gender restrictions; 4. Clinical diagnosis of AD and no other psychiatric disorders; MMSE scores between 10-27 indicate mild to moderate cognitive impairment.
Exclusion criteria
Exclusion criteria: 1. Individuals who are allergic to bacterial powder or its components; 2. Current or historical conditions of drug dependence, drug abuse, or alcohol poisoning; 3. Has serious visual, auditory, or motor impairments; 4. Have used antibiotics, probiotics, or synbiotics within the past month; 5. Conduct dietary and exercise therapy under the advice of a doctor; 6. Have a history of liver disease or severe kidney, endocrine, cardiovascular, gastrointestinal, lung, hematological, and metabolic diseases, or have received medication treatment for the aforementioned diseases; 7. History of major surgeries involving gastrectomy, gastrointestinal suture surgery, intestinal resection, and digestive system; 8. Participated in other clinical trials within the past month; Participants who are unwilling to provide personal information and do not wish to enter the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Score of the Simplified Intelligence Status Examination Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Score of Activity of Daily Living Scale;Score of the Quality of life-Alzheimer‘s Disease; | — |
Countries
China
Contacts
Public Contacthuangfu weizhong
Affiliated Hospital of Inner Mongolia Medical University
Outcome results
None listed