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Studies on the mechanism of action of adipokine C1QTNF3 in regulating concomitant anxiety in osteoarthritis of the knee

A study based on the underlying factors associated with osteoarthritis of the knee and the analysis of exercise biometric forces

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400091765
Enrollment
Unknown
Registered
2024-11-04
Start date
2024-11-05
Completion date
Unknown
Last updated
2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis

Interventions

Osteoarthritis group:None
Control group:None

Sponsors

Binzhou Medical University Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Patients with a confirmed diagnosis of osteoarthritis of the knee. 2. Can walk independently or on crutches, and can cooperate with the test. 3. Understand the basic procedure of the experiment and participate voluntarily.

Exclusion criteria

Exclusion criteria: 1.Patients who do not meet the diagnosis and inclusion criteria. 2. Patients who are unable to walk and still unable to walk with the aid of assistive devices. 3.Cognitive impairment, unable to cooperate with the examination.

Design outcomes

Primary

MeasureTime frame
Serum C1QTNF3, IL-1ß, COX2, MMP3/6/9/13, ADAMTS 4/5 mRNA and protein levels;Concentrations of mRNA and protein levels of articular cartilage C1QTNF3, IL-1ß, COX2, MMP3/6/9/13, ADAMTS 4/5 concentration concentration;Articular cartilage transcriptomics level;Serum metabolomics levels;Basic patient information;—

Countries

China

Contacts

Public ContactQianqian Fan

Binzhou Medical University Hospital

15564326283@163.com+86 155 6432 6283

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026