Abdominal pain and bloating after colonoscopy
Conditions
Interventions
A:Group taking 30 ml of simethicone before the colonoscopy.
B:Group taking 15 ml of simethicone before the colonoscopy.
C: Group taking 15 ml of simethicone before the colonoscopy and another 15 ml after the examination.
Sponsors
Zhongshan Hospital ( Xiamen ) , Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Age between 18 and 70 years; Patients undergoing colonoscopy for colorectal cancer screening or general health check-up; Voluntary participation in the study, with signed written informed consent, good compliance, and willingness to follow up.
Exclusion criteria
Exclusion criteria: 1.Pregnant, breastfeeding women, or women who do not exclude the possibility of pregnancy; 2.Abnormal liver function (total bilirubin, alanine transaminase, or aspartate transaminase = twice the upper limit of normal); 3.Serum creatinine = 1.2 times the upper limit of normal; 4.Individuals allergic to simethicone emulsion or its components; 5.Severe cardiac or pulmonary dysfunction; 6.Suffering from severe gastrointestinal diseases such as colorectal cancer, inflammatory bowel disease, or ischemic bowel disease; 7.Experiencing symptoms such as abdominal pain, bloating, or discomfort prior to the colonoscopy; 8.Patients with a history of intestinal obstruction; 9.Patients with advanced malignant tumors or other severe catabolic diseases, any unstable acute or chronic conditions; 10.Individuals who have undergone abdominal surgery within the past 6 months; 11.Patients found to have intestinal narrowing during the colonoscopy; 12.Difficulty during the colonoscopy (time to reach the cecum exceeding 10 minutes); 13.Cases with known or suspected non-compliance with the study protocol, such as alcoholism, drug dependence, or psychological disorders; 14.Participation in another drug trial within three months prior to the start of the study; 15.Any patients considered by the researchers as unsuitable for participation in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bloating, abdominal pain and abdominal discomfort;Duration of postoperative bloating; | — |
Secondary
| Measure | Time frame |
|---|---|
| Boston bowel preparation scale;Cecal intubation time;Cecal intubation rate;Adenoma detection rate; | — |
Countries
China
Contacts
Public ContactDalong Sun
Zhongshan Hospital ( Xiamen ) , Fudan University
Outcome results
None listed