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A randomised controlled clinical study of the effects of constant rate pumping of norepinephrine and phenylephrine on blood glucose and related hormones in maternal peripheral blood and fetal cord blood

A randomised controlled clinical study of the effects of constant rate pumping of norepinephrine and phenylephrine on blood glucose and related hormones in maternal peripheral blood and fetal cord blood

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400091733
Enrollment
Unknown
Registered
2024-11-01
Start date
2024-11-01
Completion date
Unknown
Last updated
2024-11-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Maternal and foetal blood glucose abnormalities after surgery

Interventions

Sponsors

Hefei Second People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Pregnant women aged between 18 and 40 years old; 2.ASA classification I-II; 3. Single term pregnancy; 4. Undergo spinal anesthesia to perform cesarean section, and collection of umbilical cord blood and maternal venous blood during the perioperative period; 5. Agree to participate in this study;

Exclusion criteria

Exclusion criteria: 1. Unable or refusing to sign the informed consent form; 2. Those who are allergic to norepinephrine or phenylephrine or are not suitable for use; 3. Those with known abnormal fetal development; 4. Patients with concomitant diabetes; 5. Those who are accompanied by severe heart, brain, liver, and kidney diseases; 6. Those who are currently using monoamine oxidase inhibitors or tricyclic antidepressants; 7. Those who have contraindications to spinal anesthesia; 8. Those who are unable to communicate and cooperate.

Design outcomes

Primary

MeasureTime frame
Blood glucose;cortisol;

Secondary

MeasureTime frame
lactate;insulin;glucagon;

Countries

China

Contacts

Public ContactJinfeng Bao

The Second People's Hospital of Hefei

252295142@qq.com+86 156 5518 0780

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026