Extranodal nasal type NK/T cell lymphoma
Conditions
Interventions
Single group allocation:PPGE chemotherapy regimen
Sponsors
the First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Newly diagnosed extranodal nasal type NK/T-cell lymphoma 2. Aged 18 to 80 years old 3. Have not received chemotherapy or radiation therapy before 4. At least one measurable or evaluable lesion 5. ECOG (Eastern Cooperative Oncology Group) score 0-2 points 6. Blood routine and liver and kidney function are generally normal: white blood cells >= 3 × 10^9/L, neutrophil count >= 1.5 × 10^9/L, platelet count >= 100 × 10^9/L; Serum creatinine = 50 mL/min; Total bilirubin <= 2 times the upper normal limit, aspartate and alanine transaminase levels <= 3 times the upper normal limit
Exclusion criteria
Exclusion criteria: 1. . Non nasal NK/T-cell lymphoma 2. Systemic central nervous system involvement 3. Previous or concomitant malignant tumors, as well as any coexisting medical issues that may lead to poor adherence to the research protocol
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Progression-Free Survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| Complete Remission Rate;Overall Response Rate;Overall Survival;Duration of response;EB-DNA;Number of subjects with treatment-related adverse events; | — |
Countries
China
Contacts
Public ContactXin Wang
the First Affiliated Hospital of Chongqing Medical University
Outcome results
None listed