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The study on biological agents for the prevention of postoperative anastomotic recurrence in Crohn's disease: a multicenter, open-label, prospective observational study.

The study on biological agents for the prevention of postoperative anastomotic recurrence in Crohn's disease: a multicenter, open-label, prospective observational study.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400091669
Enrollment
Unknown
Registered
2024-11-01
Start date
2024-11-01
Completion date
Unknown
Last updated
2024-11-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Crohn's disease

Interventions

Case series:None

Sponsors

Jinling Hospital, School of Medicine, Nanjing University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
14 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients with Crohn's disease who have undergone ileocolic resection and anastomosis. 2. Aged 18 to 75 years. 3. Have used at least one biological agent before surgery. 4. Have used at least one biological agent within 6 months post-surgery. 5. Have an anastomosis site in the ileocolic region after surgery. 6. No severe underlying diseases and no contraindications to the use of biological agents.

Exclusion criteria

Exclusion criteria: 1. Patients with malignancy associated with Crohn's disease. 2. Have used biological agents before surgery, but the names are unspecified. 3. Have used biological agents post-surgery, but the names are unspecified. 4. Lack relevant necessary information, such as unclear medical history and absence of postoperative endoscopic follow-up. 5. Have a stoma, and the ileocolic anastomosis has not been actively utilized.

Design outcomes

Primary

MeasureTime frame
endoscopic recurrence;

Secondary

MeasureTime frame
Postoperative levels of FC, HBI, albumin, and CRP;Incidence of postoperative complications;Postoperative clinical recurrence rate and surgical recurrence rate;

Countries

China

Contacts

Public ContactLi Yi

Jinling Hospital, School of Medicine, Nanjing University

liyi1860@hotmail.com+86 138 5184 3735

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026