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The correlation between the activation level of peripheral blood immune cells and changes in surface markers in patients with clinical connective tissue disease and their pathogenesis and prognosis

The correlation between the activation level of peripheral blood immune cells and changes in surface markers in patients with clinical connective tissue disease and their pathogenesis and prognosis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400091662
Enrollment
Unknown
Registered
2024-10-31
Start date
2024-10-31
Completion date
Unknown
Last updated
2024-11-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Connective tissue diseases

Interventions

CTD patient group:None
Healthy control group:None

Sponsors

Department of Rheumatology and Immunology, Tongji Hospital, Tongji Medical College, Huazhong Univers
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1: CTD patients are patients who seek treatment at Tongji Hospital affiliated with Tongji Medical College of Huazhong University of Science and Technology (initial treatment+recurrence) and meet the classification criteria of the American Society of Rheumatology in 1982 2: At the time of enrollment, the patient's age should be = 18 years old 3: Patients who are enrolled need to be aware of the biological samples they have received and voluntarily sign an informed consent form.

Exclusion criteria

Exclusion criteria: 1: Patients diagnosed with tumors within the first 6 months of this study 2: Patients with infectious diseases transmitted through blood sources (such as HIV, HBV, HCV, etc.) 3: Patients in the active phase of acute or chronic infections 4: The patient refused to comply with the requirements of this study to complete the research work 5: Any other circumstances that the researcher deems unsuitable for participation in this experiment (due to other reasons including management reasons).

Design outcomes

Primary

MeasureTime frame
Immune cell subpopulation differentiation;Changes in CD markers on the surface of immune cells;

Countries

China

Contacts

Public ContactJixin Zhong

Department of Rheumatology and Immunology, Tongji Hospital, Tongji Medical College, Huazhong Univers

jxzhong@tjh.tjmu.edu.cn+86 181 5441 2011

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026