Autism spectrum disorder
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: The autism spectrum disorder meets the diagnostic criteria for autism in the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-V) published by the American Psychiatric Association, with a definitive diagnosis issued by a hospital of tertiary care and above. Subjects were aged 2-10 years old, of either sex, with informed consent from the guardian of the subject who signed an informed consent form.
Exclusion criteria
Exclusion criteria: The exclusion were as follows: (i) previous supplementation with growth hormone, IGF-1 and other growth hormone analogues; (ii) periodontal diseases such as gingival bleeding and inflammation; and (iii) malignant tumours and acute infectious diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| oxytocin levels;growth hormone levels;Insulin-like growth factor-1 levels;Insulin-like growth factor binding protein-3 levels;Autism Behavior Checklist;Social Response Scale, second edition,SRS-2;Childhood Autism Rating Scale,CARS;Repeated Behavior Scale-Revision,RBS-R; | — |
Countries
China
Contacts
China Rehabilitation Research Center