Ovarain
Conditions
Interventions
Experimental Group:All the patients were injected with methylene blue into the ovarian cortex, uterine horns and infundibulopelvic ligaments by the surgeon1
Sponsors
Fourth Hospital of Hebei Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Women 18-80 years of age who agreed to participate in the trial and provided written informed consent. 2. Ovarian cancer was confirmed by frozen pathology before or during operation. 3. According to Suidan or Fagotti score, it is expected to be feasible to perform comprehensive staging of early ovarian cancer or R0 cytoreductive surgery for advanced ovarian cancer. 4. After clinical evaluation, the patient could tolerate anesthesia and surgery. 5. Voluntary participation in the trial (written informed consent).
Exclusion criteria
Exclusion criteria: 1. Suspected adnexal mass showed benign results by intraoperative frozen pathology. 2. Allergic reactions or other adverse reactions to previous methylene blue use. 3. Pregnancy. 4. Previous pelvic and abdominal radiotherapy history. 5. Previous history of lymphoma. 6. Previous history of lymphadenectomy. 7. Combined with other malignant tumors. 8. Patients who are not suitable for anesthesia or surgery after evaluation. 9. The investigator believes that the patients have other factors that may affect the study results and interfere with their participation in the whole study process, including past or existing physical conditions, treatment or laboratory abnormalities, etc. Or the investigator believes that participation in the study would not be in the best interest of the patient.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sentinel lymph node metastasis Detection rate;Surgical Complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| Distribution of positive sentinel lymph nodes; | — |
Countries
China
Contacts
Public ContactZhang Zhengmao
Fourth Hospital of Hebei Medical University
Outcome results
None listed