Schizophrenia, Depression
Conditions
Interventions
Sponsors
Tianjin Anding Hospital
Eligibility
Sex/Gender
All
Age
16 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) meet the DSM-V diagnostic criteria for schizophrenia; (2) using MINI screening to exclude other mental disorders; (3) aged 16-65 years old; (4) the course of disease was less than 5 years and the total duration of medication was less than two weeks; (5) Patients and their family members agreed to participate in the project and signed an informed consent form. (1) meeting the DSM-5 diagnostic criteria for depression; (2) using MINI screening to exclude other mental disorders; (3) aged 16-65 years old; (4) patients who had never been hospitalized for mental illness during the first episode; (5) taking any antidepressant or psychotropic drugs for no more than 3 days; (6) Patients and their family members agreed to participate in the project and signed an informed consent form. Healthy controls (1) using MINI screening to exclude any mental disorders; (2) There was no history of mental illness in the three generations of the father or mother; (3) aged 16-65 years old; (4) Individuals and their families agreed to participate in the project and signed an informed consent form.
Exclusion criteria
Exclusion criteria: Schizophrenia and depression (1) Complicated with serious physical diseases (such as cardiovascular, hepatic, renal, gastrointestinal diseases, etc.) and infectious diseases, and immune system diseases; (2) patients with severe nervous system diseases and mental retardation; (3) pregnant or lactating women; Healthy controls (1) patients with serious physical diseases (such as cardiovascular, liver, kidney, gastrointestinal diseases, etc.), infectious diseases and immune system diseases; (2) patients with severe nervous system diseases and mental retardation; (3) no current or long-term drug abuse or sever alcohol abuse; (4) no history of long-term use of psychiatric drugs; (4) pregnant or lactating women; (5) had immediate family members of healthy controls
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of psychiatric symptoms;Resting-state brain functional status;Combined multi-omics analysis;Brain electrophysiology; | — |
Countries
CHINA
Contacts
Public ContactJie Li
Tianjin Anding Hospital
Outcome results
None listed