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Efficacy of myofunctional therapy in reducing snoring and improving the apnea-hypopnea index in patients with obstructive sleep apnea: A cohort study in China

Efficacy of myofunctional therapy in reducing snoring and improving the apnea-hypopnea index in patients with obstructive sleep apnea: A cohort study in China

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400091588
Enrollment
Unknown
Registered
2024-10-30
Start date
2022-07-20
Completion date
Unknown
Last updated
2024-11-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obstructive sleep apnea syndrome

Interventions

observational group :None

Sponsors

The Second Affiliated Hospital of Nanchang University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: (1) age >=18 years; (2) diagnosis of OSA and refusing CPAP therapy, oral appliances, or surgery. OSA was diagnosed according to the International Classification of Sleep Disorders-3 diagnostic criteria; (3) voluntary participation with signed informed consent.

Exclusion criteria

Exclusion criteria: (1) unwillingness or inability to provide written informed consent; (2) presence of combined craniofacial malformations, regular use of hypnotic medications, hypothyroidism, previous stroke, neuromuscular disease, severe heart disease (New York Heart Association class III-IV), or severe obstructive nasal disease; (3) other types of sleep-disordered breathing, such as central sleep apnea or obesity hypoventilation syndrome (body mass index>30 kg/m2 and an awake resting carbon dioxide partial pressure >45 mmHg at sea level, after excluding other causes of hypoventilation).

Design outcomes

Primary

MeasureTime frame
apnea hypopnea index;

Secondary

MeasureTime frame
Oropharyngeal ultrasound;snore;ESS scale, Epworth Sleepiness Scale;PSQI scale, Pittsburgh sleep quality index;

Countries

China

Contacts

Public ContactLirong He

The Second Affiliated Hospital of Nanchang University

hlr-ndefy@163.com+86 181 7090 5103

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026