Postoperative delirium
Conditions
Interventions
Electrical stimulation group:Patients in the experimental group received transaural vagus nerve electrical stimulation therapy two weeks before surgery, using the optimal stimulation parameters (stimu
Sponsors
Jiangsu Cancer Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Tumor patients who are expected to undergo surgery for ovarian cancer, breast cancer, esophageal cancer, and lung cancer should receive 2 or more cycles of chemotherapy combined with paclitaxel and platinum-based drugs before surgery, and undergo elective tumor resection 4 weeks after the completion of preliminary chemotherapy; 2.ASA classification: II-III; 3.18.5kg/m2<BMI<30kg/m2; 4.Age 18-65 years old.
Exclusion criteria
Exclusion criteria: 1.Patients with a history of craniocerebral trauma, severe neurological and psychiatric diseases, and language communication disorders; 2.Patients with damaged ear skin; 3.Patients with sinus bradycardia; 4. A history of severe asthma; 5.Patients with other malignant tumors.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Delirium incidence 7 days after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of subdelirium syndrome 7 days after surgery;Postoperative pain;TNF-a level in peripheral blood;IL-6;IL-8; | — |
Countries
China
Contacts
Public ContactJianhua He
Jiangsu Cancer Hospital
Outcome results
None listed