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ED50 and ED95 of epidural ropivacaine combined with sufentanil for intraoperative analgesia in high-intensity focused ultrasound treatment of adenomyosis

The perioperative efficacy of epidural ropivacaine in high-intensity focused ultrasound treatment of adenomyosis

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400091541
Enrollment
Unknown
Registered
2024-10-30
Start date
2024-11-01
Completion date
Unknown
Last updated
2024-11-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

adenomyosis

Interventions

Experimental group:The initial concentration of ropivacaine is set at 0.065%. If analgesia is ineffective, the concentration is increased by 0.005%. If analgesia is effective, the concentration is dec

Sponsors

Suining Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1:   ASA grade I - III 2:   The lesion can be clearly displayed under ultrasound and there are no large blood vessels nearby 3:   Patients undergoing high-intensity focused ultrasound surgery 4:   18-65 years old

Exclusion criteria

Exclusion criteria: 1:   coagulation disorders 2:   skin ulceration or infection in the treatment area. 3:   acute pelvic inflammatory disease or acute infection of the reproductive system 4:   unable to communicate effectively in the perioperative period.

Design outcomes

Primary

MeasureTime frame
Half effective dose and 95% effective dose of sufentanil combined with ropivacaine;

Secondary

MeasureTime frame
Analgesic effect;Patient satisfaction;Blood pressure, heart rate, pulse, oxygen saturation, etc;modified Bromage score;Adverse reactions (tingling sensation of lower limbs, skin burns, urinary retention, nausea and vomiting, etc.);

Countries

China

Contacts

Public Contactzhang yang

Suining Central Hospital

1454268034@qq.com+86 183 4962 3682

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026