early gastric cancer
Conditions
Interventions
Tranexamic acid:During the procedure, standard solution contains TXA will be used for submucosa injection[Consisit of: 200ml 0.9% sodium chloride solution+Sodium hyaluronate solution(50mg) + methyle
control group:During the procedure, standard solution will be used for submucosa injection[Consisit of: 200ml 0.9% sodium chloride solution+Sodium hyaluronate solution(50mg) + methylene coeruleumsolu
Sponsors
Department of Gastroenterology and Hepatology,West China Hospital,Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: Patients referred for endoscopic resection of a gastric mucosal leision with a diamater ranges from 2-5cm.Age > 18 years
Exclusion criteria
Exclusion criteria: 1.allergic to tranexmic acid; 2.a history of venous thrombosis, pulmonary embolism, stroke, and coronary artery disease; 3.Severe chronic renal failure(eGFR <30 mL/min/1.73 m2); 4.submucosal tumor or deep submucosal leision; 5.Inherited or acquired coagulation disorders that may affect bleeding risk; 6.receive anticoagulant therapy such as aspirin, clopidogrel, or warfarin and cannot stop taking it before surgery; 7.can not afford consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the frequency of using hemostatic forceps to stop intraprocedrual bleeding; | — |
Secondary
| Measure | Time frame |
|---|---|
| success rate of ESD;operation time;rate of ESD;scores of difficulty of hemostasis by endoscopist ; | — |
Countries
China
Contacts
Public ContactJinlin Yang
West China Hospital,Sichuan University,Chengdu,China
Outcome results
None listed