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Study of Remimazolam besylate in the anesthesia management of patients with cirrhosis during gastroscopy

Study of Remimazolam besylate in the anesthesia management of patients with cirrhosis during gastroscopy

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400091513
Enrollment
Unknown
Registered
2024-10-29
Start date
2024-11-01
Completion date
Unknown
Last updated
2024-11-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

liver cirrhosis

Interventions

Remazolam group ( Group R):Intravenous injection of remazolam besylate
Propofol group (Group P):Intravenous injection of propofol

Sponsors

Beijing Ditan Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients aged 18-65 years old, regardless of gender. Patients with Child-Pugh below grade A or B,undergoing gastroscopy. American Society of Anesthesiologists ASA Class II-III. BMI 18.5-30kg/m2. Patients who are told to volunteer for the trial and signed informed consent forms. Expected survival > 6 months.

Exclusion criteria

Exclusion criteria: Patients who explicitly refuse to participate in the study. Patients with a history of serious heart, brain, lung, kidney and metabolic diseases. Patients with a history of recovery from abnormal surgical anesthesia. Electrocardiogram: heart rate 180mmHg and/or diastolic blood pressure >110mmHg in hypertensive patients, or <90/60mmHg in hypotensive patients. Patients with neuromuscular system diseases or mental diseases. Patients suspected abuse of narcotic analgesics or sedatives. Patients that the researcher considers inappropriate to participate in this study.

Design outcomes

Primary

MeasureTime frame
Incidence of hypotension;

Secondary

MeasureTime frame
Low oxygen saturation, airway obstruction, respiratory depression, apnea, bradycardia, tachycardia and other adverse reactions;Satisfaction rating;Postoperative adverse reactions;Frequency and dose of vasoactive drugs;

Countries

China

Contacts

Public ContactZhao jinying

Beijing Ditan Hospital, Capital Medical University

469115796@qq.com+86 173 2094 3546

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026