Skip to content

Effect of Shenfu injection on cardiac function in elderly patients with cardiovascular disease during general anesthesia

Effect of Shenfu injection on cardiac function in elderly patients with cardiovascular disease during general anesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400091508
Enrollment
Unknown
Registered
2024-10-29
Start date
2024-11-01
Completion date
Unknown
Last updated
2024-11-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular disease

Interventions

Shenfu Group:Before induction of anesthesia, 50ml of Shenfu injection was diluted with 0.9% saline 100ml and then infused intravenously,the infusion was completed within 15 minutes
Control Group:Before induction of anesthesia, 0.9% normal saline (100ml) was given intravenously,the infusion was completed within 15 minutes

Sponsors

Affiliated Hospital of Traditional Chinese Medicine of Southwest Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 95 Years

Inclusion criteria

Inclusion criteria: 1.Patients undergoing elective non-cardiac surgery under general anesthesia; 2.Age =65 years, ASA Grade II-III; 3.Patients with hypertension or coronary heart disease can tolerate general anesthesia after treatment; 4.The estimated operative time was =1 hour; 5.Patients volunteered to participate in the study and signed the informed consent.

Exclusion criteria

Exclusion criteria: 1.Patients with mental illness, severe cognitive impairment or with language and communication disorders; 2.Long-term use of sedative-hypnotic drugs; 3.Complicated with severe liver and kidney disease; 4.Blood pressure =180/110mmhg; 5.Difficult endotracheal intubation; 6.Patients who are allergic or have contraindications to shenfu, general anesthetic or its components.

Design outcomes

Primary

MeasureTime frame
Myocardial contraction index;Stroke volume;

Secondary

MeasureTime frame
Heart rate;Blood pressure;Peripheral vascular resistance;Cardiac output;Stroke volume variation;

Countries

China

Contacts

Public ContactZhang Ying

Affiliated Hospital of Traditional Chinese Medicine of Southwest Medical University

zhangying021210@163.com+86 135 5172 0908

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026