Skip to content

The effects of transcranial direct current stimulation combined with deep muscle stimulation on hand dysfunction and cortical excitability after stroke: a randomised controlled trial.

The effects of transcranial direct current stimulation combined with deep muscle stimulation on hand dysfunction and cortical excitability after stroke: a randomised controlled trial.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400091505
Enrollment
Unknown
Registered
2024-10-29
Start date
2024-11-15
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

Test group:Deep muscular stimulation + Transcranial direct current stimulation
Control group:Deep muscular stimulation + Transcranial direct current sham stimulation

Sponsors

The First Hospital of Shanxi Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. First-time onset, meeting the diagnostic criteria for cerebral infarction and cerebral hemorrhage as outlined in the "Diagnostic Criteria for Major Cerebrovascular Diseases in China 2019," and diagnosed as a unilateral stroke patient via cranial MRI or head CT; 2. Age between 18 and 75 years old; 3. Mild to moderate hand function impairment (with noticeable flexion movement in the fingers), MAS grading =3; 4. Edinburgh Dominant Hand Test results indicate right-handedness. 5. The patient or legal guardian has signed an informed consent form.

Exclusion criteria

Exclusion criteria: 1. Presence of bleeding, burns, inflammation, or joint deformities in the hands; 2. Severe heart, liver, or kidney diseases; psychological disorders; skeletal diseases; infectious diseases; peripheral neuropathy; epilepsy; or malignant tumors; 3. Cognitive impairment (MMSE score < 20) and inability to perform simple task instructions; 4. Individuals with implanted cochlear implants, metal dentures, pacemakers, or other electronic devices that may be triggered by electromagnetic fields; 5. Individuals taking medications that improve central nervous system function and affect muscle tone; 6. Individuals with communication difficulties, aphasia, or severe articulation disorders; 7. Individuals with unilateral neglect, severe visual impairments, or visual perception disorders.

Design outcomes

Primary

MeasureTime frame
motor evoked potential (MEP);Fugl Meyer(FMA wrist-hand);

Secondary

MeasureTime frame
Jebsen-Taylor(JHFT);Modified Barthel Index;Mini-Mental State Examination(MMSE);

Countries

China

Contacts

Public ContactLian Tao

The First Hospital of Shanxi Medical University

taolian1000@126.com+86 351 398 6070

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026