Skip to content

Okra eyelid patch versus sodium hyaluronate combined with ofloxacin eye drop in the treatment of meibomian gland dysfunction: a randomized controlled trial

The effects of okra eyelid patch in the treatment of meibomian gland dysfunction-related dry eye

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400091496
Enrollment
Unknown
Registered
2024-10-29
Start date
2022-09-29
Completion date
Unknown
Last updated
2024-11-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dry eye

Interventions

two:okra eye patch
two:ofloxacin eye drops (Santen Pharmaceutical Co., Ltd.) combined with 0.3% sodium hygroscopicity eye drops (S Santen Pharmaceutical Co., Ltd.)

Sponsors

Zhongshan Hospital Affiliated to Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
26 Years to 74 Years

Inclusion criteria

Inclusion criteria: 1. Patients with MGD associated with dry eye admitted to the Ophthalmology Clinic of Zhongshan Hospital, Fudan University; 2. Age: 18-80 years old; 3. No gender limit; 4.All subjects signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Suffering from glaucoma, tear duct obstruction, keratitis, iritis and other eye diseases and a history of eye trauma; 2. History of corneal contact lens wear in the last 1 month; 3. Lipiflow meibomian gland heat pulsation treatment, intense pulsed light therapy, and meibomian gland probing were performed in the last 1 month; 4. History of eye surgery like cataract surgery, refractive surgery in the last 3 months; 5. Systemic diseases such as severe skin diseases, systemic lupus erythematosus and dry syndrome; 6. Allergy to okra ingredients; 7. Using systemic antibiotics, glucocorticoids or immunosuppressants; 8. Pregnancy or lactation.

Design outcomes

Primary

MeasureTime frame
OSDI questionnaire score;

Secondary

MeasureTime frame
Slit-lamp biomicroscopic signs;Schimer I test;Tear film break-up time;Corneal fluorescein staining;OQAS II;Corneal confocal microscopy test;Pittsburgh Sleep Quality Index (PSQI), self-rating Anxiety scale (SAS), self-rating Depression scale (SDS);Adverse Reaction Reports;

Countries

China

Contacts

Public ContactXiaoping Ma

Zhongshan Hospital Affiliated to Fudan University

xiaopingma@126.com+86 136 8197 6151

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026