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A randomized controlled study of balancing psychotherapy and cognitive behavioral therapy in adolescents with MDD: Based on genetic and imaging analysis

A randomized controlled study of balancing psychotherapy and cognitive behavioral therapy in adolescents with MDD: Based on genetic and imaging analysis

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400091494
Enrollment
Unknown
Registered
2024-10-29
Start date
2024-08-26
Completion date
Unknown
Last updated
2024-11-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Major depressive disorder

Interventions

balancing psychotherapy group:balancing psychotherapy was completed once a week for 8 weeks
cognitive behavioral therapy group:Cognitive behavioral therapy was completed once a week for 8 weeks

Sponsors

Zhongda Hospital, Southeast University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
12 Years to 18 Years

Inclusion criteria

Inclusion criteria: (1) meeting the DSM-5 criteria for mild or moderate depression; (2) aged between 12 and 18 years; (3) not receiving medication or having been on stable medication for at least two weeks prior to and throughout the study; (4) not having received psychotherapy, or not having received psychotherapy for at least two months before the study.

Exclusion criteria

Exclusion criteria: (1) comorbidding anxiety disorders, obsessive-compulsive disorder, bipolar disorder, schizophrenia, or other psychiatric disorders; major depressive disorder with psychotic symptoms such as hallucinations; (2) moderate to high suicide risk; (3) severe functional impairment that precludes the ability to complete psychological therapy; (4) substance abuse or dependence on psychoactive substances.

Design outcomes

Primary

MeasureTime frame
Hamilton Depression Scale;

Secondary

MeasureTime frame
Beck Depression Inventory;Beck Anxiety Inventory;World Health Organization Five-item Well-Being Index;Adolescent Self-Injurious Behavior Questionnaire;Goal Pursuit Scale;Interpersonal Relationship Scale;Automatic Thoughts Questionnaire;functional magnetic resonance imaging;functional near-infrared spectroscopy;

Countries

China

Contacts

Public ContactYonggui Yuan

Zhongda Hospital, Southeast University

yygylh2000@sina.com+86 139 1393 9082

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026