acute oral poisoning
Conditions
Interventions
Out-patient Group:After the first dose of 50g, take 20g every 4-6 hours
In-patient Group 1:After the first dose of 100g, 20g was administered at 4-6 h intervals and continued for several days
In-patient Group 2:After the first dose of 50g, 20g was administered at 4-6 h intervals and continued for several days
Sponsors
Shandong Provincial Hospital Affiliated to Shandong First Medical University
Eligibility
Sex/Gender
All
Age
14 Years to No maximum
Inclusion criteria
Inclusion criteria: ? Patients with acute oral poisoning or overdose; ? age =14 years old; ? Informed consent was obtained from patients or their guardians. ? If the patient has disturbance of consciousness, the drug can be administered through an indwelling gastric tube with airway protection and the informed consent of the guardian.
Exclusion criteria
Exclusion criteria: ? Alcohol (e.g., ethanol, methanol, and diols, e.g., ethylene glycol), inorganic salts (e.g., sodium chloride), metals and their inorganic compounds (e.g., lithium, iron, or other heavy metals, e.g., lead or mercury), organic solvents (e.g., acetone, dimethyl sulfoxide, gasoline), acids and bases, cyanide poisoning; ? Exposure to toxins that inhibit gastrointestinal peristalsis (such as anticholinergic drugs, opioids, etc.); ? Disturbance of consciousness, no swallowing reflex, no airway protection; ? Gastrointestinal corrosion or bleeding, gastrointestinal damage or suspected perforation; ? Recurrent vomiting; ? Informed consent could not be obtained.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mortality rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood/Urine toxin concentration;Blood routine examination;Liver and kidney function test, and biochemistry;Coagulation function;Myocardial marker; | — |
Countries
China
Contacts
Public ContactZhang Xingguo
Shandong Provincial Hospital Affiliated to Shandong First Medical University
Outcome results
None listed