Periodontitis
Conditions
Interventions
periodontal group(Grade A): None
Health group: None
Periodontal group(Grade B): None
Periodontal group(Grade C): None
Sponsors
Bejing Tongren Hospital, Capital Medical Uniersity
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Periodontitis patient group: Ages 18-60, with gingival inflammation, bleeding on probing, probing depth of =6mm, clinical attachment loss of =5mm, radiographic evidence of alveolar bone loss to at least the middle 1/3 of the root, vertical bone loss of =3mm, and no more than 4 teeth lost due to periodontitis, classified into grades A, B, and C according to the 2018 international classification of periodontal diseases. 2. Periodontally healthy group: Ages 18-60, without gingival inflammation, no bleeding on probing, probing depth of <3mm, no clinical attachment loss, and no radiographic evidence of alveolar bone loss.
Exclusion criteria
Exclusion criteria: 1. Women who are pregnant or nursing; 2. Individuals who smoke more than 10 cigarettes per day; 3. Patients with uncontrolled severe systemic diseases (such as: hypertension, diabetes, heart disease); 4. Those who have taken corticosteroids, antimicrobial, or antibiotic medications within the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Immune cell quantity ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Gene Expression in Immune Cells; | — |
Countries
China
Contacts
Public ContactLin Jiang
Beijing Tongren Hospital, Capital Medical University
Outcome results
None listed