Research and development of non-invasive drug delivery pathways for narcotic drugs - Clinical application research based on digital simulation technology

Research and development of non-invasive drug delivery pathways for narcotic drugs - based on digital simulation, animal model and clinical application research

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400091480

Enrollment

Unknown

Registered

2024-10-29

Start date

2024-06-01

Completion date

Unknown

Last updated

2024-11-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

Drop group:2ug/kg dexmethomidine nasal drops

ultrasonic atomization group:2ug/kg dexmethomidine ultrasonic atomization

Anesthesia non-invasive administration group:Non-invasive administration of 2ug/kg dexmethomidine in nasal anesthesia

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: a) Age 18 = years old, mentally sound people, regardless of gender b) understand the test, agree and sign the consent; c) Not participating in other drug trials; d) No known chronic diseases such as high blood pressure, diabetes, heart disease, asthma

Exclusion criteria

Exclusion criteria: a) Allergic to intervention drugs; b) Participants who do not agree to participate in the experiment.

Design outcomes

Primary

Measure	Time frame
dexmedetomidine plasma concentration;	—

Secondary

Measure	Time frame
RAMSAY score;blood pressure;heart rate;blood oxygen;BIS;	—

Countries

CHINA

Contacts

Public ContactSun yanyuan

Shenzhen University General Hospital

602970445@qq.com+86 135 7258 0722

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026