Excision of intramedullary tumors and discectomy and spinal canal decompression and vertebral bone graft fusion
Conditions
Interventions
Experimental group:Cypofol was used for induction and maintenance of general anesthesia in experimental groups
Control group:In control group, propofol was used for induction and maintenance of general anesthesia
Sponsors
The first affiliated hostipal of nanchang university
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. ASA grade I-III, body mass index 18-24 kg/m^2; 2. The function of heart, lung, liver and kidney are normal before operation; 3. Patients who agreed to participate in this study were selected to undergo intraoperative neurophysiological monitoring of spinal surgery;
Exclusion criteria
Exclusion criteria: 1.Suffering from epilepsy, neuromuscular disorders such as myasthenia gravis; 2.Preoperative use of antidepressants, sedatives, and alcoholism; 3. Skull defects, elevated intracranial pressure, intracranial implants, artificial pacemaker; implants; 4.Refusal to participate in the study, allergy to narcotic drugs; 5.Accompanied by speech and sensory dysfunction; 6. Perceived unsuitability for participation in the study;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The current intensity and amplitude of MEP were induced for the first time; | — |
Secondary
| Measure | Time frame |
|---|---|
| The amplitudes and latencies of SEP and MEP at different time points;HR, BP, SPO2, BIS;;Time of first induced MEP;The operation time, anesthesia time;Cyclopofol or propofol dosage;Injection pain, bradycardia, hypotension and movement during the operation and other adverse reactions;mini-mental state examination (MMSE) score; | — |
Countries
China
Contacts
Public ContactSun wen jie
The first affiliated hostipal of nanchang university
Outcome results
None listed