Stroke
Conditions
Interventions
study group:Tracheostomy performed within 72 hours after intubation
control group:Tracheostomy performed more than 72 hours after intubation.
Sponsors
The Second Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1) ICU stroke patients in a coma after decompressive surgery (GCS < 9) 2) Diagnosis of one of the following: a. Non-traumatic acute ischemic stroke (AIS) b. Non-traumatic intracerebral hemorrhage (ICH) c. Non-traumatic subarachnoid hemorrhage (SAH) 3) Legal representative signs the informed consent form 4) Major indications for tracheostomy (at least one of the following): a. Frequent need for suctioning b. Central nervous system-related respiratory insufficiency c. Aspiration or risk of aspiration due to dysphagia 5) Endotracheal intubation with mechanical ventilation 6) Age = 18 years.
Exclusion criteria
Exclusion criteria: 1) Severe underlying respiratory disease: severe obstructive pulmonary disease 2) Pregnancy 3) Stroke involving the respiratory center (e.g., brainstem hemorrhage leading to abnormal respiratory rhythm or rate) 4) Contraindications to tracheostomy 5) BMI = 35 kg/m² 6) Informed consent not signed 7) Intubation with mechanical ventilation for more than 3 days 8) Existing or anticipated life-threatening emergency prior to tracheostomy 9) Family unwilling to continue aggressive treatment for 3 weeks, potentially leading to treatment withdrawal
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative pulmonary complication rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Ventilator free days at 28 days;28-day mortality;In-hospital mortality;Length of hospital stay;Length of ICU stay; | — |
Countries
China
Contacts
Public ContactYun Sun
The Second Affiliated Hospital of Anhui Medical University
Outcome results
None listed