Pregnancy
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Women aged 18 to 45 years old (including pregnant women and normal non-pregnant women as a control group); (2) No serious liver, kidney, heart and other organ diseases; (3) Pregnant women in the first trimester (=12 weeks), the second trimester (13-27 weeks), and the third trimester (28-farrowing weeks) were included.
Exclusion criteria
Exclusion criteria: (1) Suffering from coagulation disorders or other serious chronic diseases; (2) Use of anticoagulant and antiplatelet drugs such as heparin, warfarin, aspirin, clopidogrel in the past three months; (3) Hereditary or acquired coagulation factor deficiency; (4) Patients with severe abnormal liver function; (5) Those who have used estrogen, progesterone, and glucocorticoid drugs in the past three months; (6) Patients with gestational hypertension, chronic hypertension, and severe cardiovascular and cerebrovascular diseases; (7) IVF pregnancy; (8) Patients with autoimmune diseases that affect coagulation function (such as systemic lupus erythematosus, antiphospholipid antibody syndrome, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Thromboelastography; | — |
Countries
China
Contacts
Department of Blood transfusion,Women's Hospital School of Medicine Zhejiang University