Efficacy of Enhanced Preoxygenation Protocols in Mitigating Hypoxemia during Propofol Sedation for Gastrointestinal Endoscopic Procedures

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400091389

Enrollment

Unknown

Registered

2024-10-28

Start date

2024-11-01

Completion date

Unknown

Last updated

2024-11-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hypoxemia

Interventions

Intervention Group :The patients in Group Intervention were preoxygenated with 8 TVBs in 1 minute using a close fitting mask connected to the anaesthesia machine via a respiratory circuit at an oxygen

Non-intervention Group :There was no intervention in the non-intervention group. The anaesthetist responsible for sedation was unaware of the details of the study. A separate researcher observed and r

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Age 18 to 75 years; 2. BMI =18.5 kg/m2; 3. ASA grade ?-?; 4. Diagnostic sedation gastroscopy.

Exclusion criteria

Exclusion criteria: 1. Upper respiratory infection or lung disease such as COPD 2. History of alcohol/drug abuse; 3. Difficult airway; 4. Inability to keep the mask closed, such as bearded or toothless face; 5. Pregnancy.

Design outcomes

Primary

Measure	Time frame
Incidence of hypoxemia;	—

Secondary

Measure	Time frame
Time to first hypoxemia;Minimum SpO2;Incidence of airway interventions;	—

Countries

China

Contacts

Public ContactBo Lulong

Shanghai Changhai Hospital

bartbo@smmu.edu.cn+86 138 1728 3189

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026