Airway stenosis
Conditions
Interventions
opioid-free anaesthesia group :During anesthesia induction, the opioid-free anaesthesia group received intravenous injections of 0.2mg/kg of esketamine and 2mg/kg of lidocaine as analgesic drugs. Duri
control group:During anesthesia induction, the control group received intravenous injection of sufentanil 0.4ug/kg and physiological saline. During the surgery, the control group received continuous i
Sponsors
The First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) Patients with airway stenosis who plan to undergo airway intervention therapy (diagnosed with airway stenosis through chest CT or bronchoscopy); (2) Age = 18 years old; (3) American Society of Anesthesiologists (ASA) classification II~IV patients.
Exclusion criteria
Exclusion criteria: (1)Patients with severe mental illnesses; (2) Merge serious internal and external diseases (such as poorly controlled hypertension Poorly controlled diabetes, severe heart, liver, kidney, lung dysfunction or any of the Esketamine or Medication contraindications for lidocaine); (3) Allergic to local anesthetics such as ketamine or amide; (4) Suffering from Patients with heart failure and severe heart conduction block; (5) Long term use of opioid drugs or chronic pain.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the timeweighted average Spo2/Fio2 ratio during the initial postoperative hour; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time weighted average of SpO2/FiO2 ratio 12 hours after surgery;Intraoperative vital signs;Numerical rating scale for pain assessing;Postoperative use of painkillers;Postoperative nausea and vomiting incidence rate;Postoperative use of antiemetic drugs;Incidence of postoperative hypoxemia;The amount of anesthetic drugs used during the operation;Patient operation time, anesthesia time, extubation time, PACU dwell time; | — |
Countries
China
Contacts
Public ContactGangming Wu
The First Affiliated Hospital of Chongqing Medical University
Outcome results
None listed