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Intestinal protection strategies for prevention of necrotizing enterocolitis in preterm infants: a retrospective cohort study

Intestinal protection strategies for prevention of necrotizing enterocolitis in preterm infants: a retrospective cohort study

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400091357
Enrollment
Unknown
Registered
2024-10-28
Start date
2024-11-01
Completion date
Unknown
Last updated
2024-11-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Necrotizing enterocolitis of the newborn

Interventions

Intestinal protection group (Intestinal protection strategy):None
Control group (Routine use of antibiotics, no use of probiotics and no routine glycerin enemas):None

Sponsors

Affiliated hangzhou first people's hospital, zhejiang university school of medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 1 Years

Inclusion criteria

Inclusion criteria: 1.The study center enrolled preterm infants weighing less than 1500g between January 2020 and December 2023.

Exclusion criteria

Exclusion criteria: 1.Preterm infants with a birth weight equal to or greater than 1500 grams at each research center were excluded. Those with a birth weight less than 1500 grams either expired within 24 hours of birth or discontinued treatment, and infants exhibiting severe malformations and major congenital abnormalities such as gastrointestinal diseases, cyanotic congenital heart disease, etc., were also excluded.

Design outcomes

Primary

MeasureTime frame
Incidence of necrotizing enterocolitis in newborns;Surgical rate for neonatal necrotizing enterocolitis;

Secondary

MeasureTime frame
Occurrence of late-onset sepsis;Total enteral feeding time;Duration of residence;The occurrence of cholestasis;mortality rate;Occurrence of intracranial hemorrhage;Prevalence of bronchopulmonary dysplasia;Incidence of retinopathy in premature infants;

Countries

China

Contacts

Public Contacthonghui

Affiliated hangzhou first people's hospital, zhejiang university school of medicine

408140565@qq.com+86 18258488243

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026