Hypertensive disorders of pregnancy
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Gestational hypertension, preeclampsia, pregnancy with chronic hypertension, chronic hypertension with preeclampsia. The specific criteria are as follows: (1) Hypertension during pregnancy: hypertension appears for the first time after 20 weeks of pregnancy, systolic blood pressure = 140mmHg and/or diastolic blood pressure = 90mmHg; Urine protein test is negative. (2) Preeclampsia: systolic blood pressure = 140 mmHg and/or diastolic blood pressure = 90 mmHg after 20 weeks of pregnancy, accompanied by any of the following: urine protein quantification =0.3g/24 h, or urine protein/creatinine ratio =0.3, or random urine protein = (+); No proteinuria but with involvement of any one of the following organs or systems: heart, lungs, liver, kidneys and other important organs, or abnormal changes in the blood, digestive and nervous systems, placenta-fetal involvement, etc. (3) Pregnancy complicated with chronic hypertension: pregnant women have secondary or primary hypertension of various reasons. (4) Chronic hypertension with preeclampsia: pregnant women with chronic hypertension have no proteinuria before 20 weeks of pregnancy, and have urine protein quantification =0.3 g/24 h or random urine protein = (+) after 20 weeks of pregnancy, clean midstream urine and exclude confusion when urine is less and urine specific gravity is increased; or proteinuria before 20 weeks of gestation, and the amount of protein in the urine increases significantly after 20 weeks of gestation; or any of the above manifestations of severe preeclampsia, such as a further increase in blood pressure. 2. All of them are singleton pregnancies with normal fetal development; 3. Under the age of 45; 4. Voluntarily participate in this study, and give informed consent to the content of the study, and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Severe preeclampsia, eclampsia, chronic hypertension complicated by severe eclampsia. The specific criteria are as follows: 1)Severe pre-eclampsia: pregnant women with preeclampsia have any of the following manifestations: (1) Uncontrollable continuous increase in blood pressure: systolic blood pressure = 160 mmHg and/or diastolic blood pressure = 110 mmHg; (2) persistent headache, visual disturbances or other central nervous system abnormalities; (3) persistent epigastric pain and hepatic subcapsular hematoma or liver rupture; (4) Abnormal aminotransferase level: blood alanine aminotransferase (ALT) or aspartate aminotransferase (AST) level is elevated; (5) Impaired renal function: urine protein quantification >2.0g/24 h; oliguria (24-hour urine output 106 micromol/L; (6) Hypoproteinemia with ascites, pleural effusion or pericardial effusion; (7) Hematologic abnormalities: platelet count is continuously declining and lower than 100×109/L; microvascular hemolysis with anemia, elevated serum lactate dehydrogenase (LDH) levels, or jaundice; (8) heart failure; (9) pulmonary edema; (10) Fetal growth restriction or oligohydramnios, fetal death in utero, placental abruption, etc. 2).Eclampsia: tonic tics that cannot be explained by other causes occur on the basis of preeclampsia, which can occur prenatal, intrapartum or postpartum, or when there are no clinical manifestations of preeclampsia. 3) Chronic hypertension complicated by severe eclampsia: 2. Pregnant women with a history of preterm birth, placenta previa, threatened preterm birth and other high-risk pregnancies may induce uterine contractions and increase the risk of preterm birth due to excessive exercise. 3. Patients with severe psychological and cognitive impairment, intellectual disability, language communication disorder, unable to complete this study; 4. Patients with psychiatric and neurological disorders; 5. Diabetes mellitus complicated with pregnancy; 6. Pregnant women with hyperthyroidism or heart, blood vessel and lung diseases may increase the burden of pre-existing diseases due to excessive exercise. 7. Pregnant women after 30 weeks in the third trimester of pregnancy, excessive exercise in the third trimester may increase the risk of premature rupture of membranes, which will pose a threat to the health of the mother and baby.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood pressure;Maternal and infant outcomes; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adherence to exercise;Six-minute walk test;Disease knowledge and motor self-efficacy scores;Patient satisfaction; | — |
Countries
China
Contacts
Shenzhen Guangming District People's Hospital