hypertensive disorders of pregnancy
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Criteria for inclusion of case groups: Included patients with a diagnosis consistent with preeclampsia: Systolic blood pressure =140mmHg and/or diastolic blood pressure =90mmHg after 20 weeks of gestation, accompanied by urinary protein = 0, 3 g/24h, or random urinary protein (+), or without proteinuria, but with any of the following: (1) Thrombocytopenia (platelet < 100×109/L); (2) Liver function damage (serum transaminase level is more than 2 times the normal value); (3) Renal function impairment (creatinine level greater than 1.1mg/dl or more than 2 times the normal value); (4) Pulmonary edema; (5) New abnormalities of the central nervous system or visual disturbances; (6) signed the informed consent. Criteria for inclusion of normal pregnancy controls: (1) no complications or complications; (2) Patients who delivered cesarean section in Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology; (3) signed informed consent.
Exclusion criteria
Exclusion criteria: The exclusion criteria for included patients were: (1) Hypertension during pregnancy, chronic hypertension during pregnancy, chronic hypertension complicated with preeclampsia and other hypertensive diseases during pregnancy other than preeclampsia. (2) Those who are unable or unwilling to sign informed consent, or the researcher considers that inclusion of the researcher is not appropriate for other reasons. The exclusion criteria for normal pregnancy controls were: (1) To exclude all complications and complications of pregnancy, especially placenta derived diseases such as placenta previa, fetal growth restriction, pregnancy with oligohydramnios, etc. (2) Those who are unable or unwilling to sign informed consent, or the researcher considers that inclusion of the researcher is not appropriate for other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood pressure; | — |
Secondary
| Measure | Time frame |
|---|---|
| Urinary protein; | — |
Countries
China
Contacts
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology